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Known Issue: Unable to activate Microsoft Office for Mac
MIcrosoft Office for Mac is unable to activate
Known Issue: Unable to launch Outlook (.ost in use and cannot be accessed)
This is caused by the corruption of Outlook's profile file. You will need to reset your Outlook following instructions included in the Related Articles section on the right. If you had any shared mailboxes included in your Outlook, you will need to add them there again after resetting Outlook. See Related Articles section on the right.
Why am I unable to sign into Microsoft 365 Portal?
Troubleshooting steps for problems related to signing into Microsoft 365 portal.